The micro-blogging site went down at approximately 11:45 a.m. ET Thursday, according to Twitter’s Status page. The site was still down at 1 p.m. Thursday.
Users from several different parts of the country report that they are without Twitter service.
The crash comes the day before the Opening Ceremonies for the Summer Olympics.
Twitter has created a special page to aggregate the most interesting tweets from Olympic athletes and their families and coaches, as well as from reporters and sports commentators.
The Twitter.com/#Olympics page, at https://twitter.com/olympics, is slated to go live today.
The latest outage comes just a few weeks after Twitter went down twice on June 21.
That outage, blamed on a cascading bug in one of Twitter’s infrastructure components, affected Twitter and third party apps running on Android- and Apple iOS-based devices.